The effects of licorice mucoadhesive patches (Aftogel®) on the results of nasopharyngeal swab real-time PCR test of SARS-CoV-2: a randomized triple-blind placebo-controlled clinical trial

Background and objectives: Up to present no efficacious antiviral medications have been discovered in order eradicate SARS-CoV-2 nasopharyngeal tract. In this article, the aim is evaluate effectiveness of a new herbal drug product called Aftogel patch, which contains licorice extract, eradication novel coronavirus secretions patients. Methods: triple-blind randomized clinical trial, 125 patients with positive real-time PCR for stage 0 and/or 1 COVID-19 were studied two separate groups, namely interventional placebo, they used placebo patches, respectively. At end study, results test aforementioned groups assessed compared. Results: Following application Aftogel, Real-time was converted negative 53.97% significantly higher than that groups. (27.40%, P= 0.003). Conclusion: It seems mucoadhesive patch (Licorice extract) effective has colonized area. Hence, potential evaluation as prophylactic agent against COVID-19.